• Birthplace: Minneapolis, Minnesota, USA
• Age: 44
• Height: 157 cm
• Weight: 55 kg
• Website: N/A

Rachael Leigh Cook (born October 4, 1979) is an American actress, model, voice artist, and producer. She has starred in the films The Baby-Sitters Club (1995), She's All That (1999), and Josie and the Pussycats (2001), and in the television series Into the West and Perception. She is also the voice behind various characters in Robot Chicken and Tifa Lockhart in the Final Fantasy series, starting with the English version of the film Final Fantasy VII: Advent Children.

Rachael Leigh Cook was born in Minneapolis, Minnesota, the daughter of JoAnn, a cooking instructor and weaver, and Thomas H. Cook, a social worker and former stand-up comedian. She is of part Italian descent. Cook first appeared in a public service announcement for foster care at seven years of age, and began working as a child print model at the age of 10, most notably in nationwide advertisements for Target and appearing on the boxes of Milk-Bone dog biscuits. She attended Clara Barton Open School, Laurel Springs School, and Minneapolis South High School.

Rachael Leigh Cook was born in Minneapolis, Minnesota, the daughter of JoAnn, a cooking instructor and weaver, and Thomas H. Cook, a social worker and former stand-up comedian. She is of part Italian descent. Cook first appeared in a public service announcement for foster care at seven years of age, and began working as a child print model at the age of 10, most notably in nationwide advertisements for Target and appearing on the boxes of Milk-Bone dog biscuits. She attended Clara Barton Open School, Laurel Springs School, and Minneapolis South High School.

Cook owns her own production company, Ben's Sister Productions (in reference to her younger brother Ben Cook, an aspiring filmmaker).

Cook provided the voice for Chelsea Cunningham on the Kids' WB animated series Batman Beyond and in the animated film Batman Beyond: Return of the Joker. Cook voiced Tifa Lockhart in the video games Kingdom Hearts II, Dirge of Cerberus: Final Fantasy VII and Dissidia 012 Final Fantasy, as well as the CG movie Final Fantasy VII Advent Children. In 2011, she voiced the character of Jaesa Willsaam in the MMO game, Star Wars: The Old Republic. Cook's latest voice-over role is for the video game Yakuza in which she voices the role of Reina.

Cook first gained national attention in 1997, when she was featured in the famous This Is Your Brain on Drugs PSA television advertisement, in which she proceeds to destroy a kitchen with a frying pan as she lists the important things in life that heroin harms.

In 2011, she was selected by the Obama administration as a Champion of Change for Arts Education.

In June 2012, she began to award a small scholarship to students between ages 14 and 19. The scholarship helps pay for career classes, mentoring programs, and other school fees.

In 2017, Rachael Leigh Cook reprised her "This Is Your Brain on Drugs" role twenty years later for a PSA by the Drug Policy Alliance critiquing the War on Drugs and its contribution to mass incarceration, structural racism and poverty. The ad was posted to YouTube on April 20, 2017 in recognition of 4/20.

Cook married actor Daniel Gillies in August 2004, whom she dated since 2001. They have two children: a daughter born September 2013, and a son born April 2015. The couple announced their separation in June 2019.